Comparison of intrathecal sufentanil and morphine in addition to bupivacaine for caesarean section under spinal anesthesia
Abstract
Background: Co-administration of small dose of opioids with bupivacaine for spinal analgesia is advocated because of synergistic action between local anaesthetics and opioids, leading to reduction in doses, intraoperative discomfort and postoperative analgesic requirement.
Aim: We compared the effects of intrathecal sufentanil with intrathecal morphine, when added to bupivacaine for caesarean sections.
Method: Sixty ASA I and II parturients, undergoing caesarean section under spinal anaesthesia, were randomly allocated into three groups of 20 each to receive either injection (inj.) bupivacaine 12 mg (Group I), which was labelled as the control group; inj. bupavacaine 12mg + inj sufentanil 10mcg (Group II) or inj. bupavacaine 12 mg + morphine 0.2mg (Group III) in a double blind clinical trial. The parameters studied were the time of onset, sensory level of the block achieved, total duration of analgesia, any need of rescue analgesics, maternal side effects and foetal outcome..