A comparison of hemodynamic changes during laryngoscopy and endotracheal intubation by using three modalities of anesthesia induction

  • Masoud Lahsaee Shiraz Anesthesiology and Critical Care Research Center
  • Hamid Kamalipour Laparoscopy Research Center
  • Zahra Ajeli Department of Anesthesiology
  • Karmella Kamali Department of Radiology Shiraz University of Medical Sciences, Shiraz (Iran)
Keywords: Thiopental, Propofol, Laryngoscopy, Endotracheal intubation, Anesthesia

Abstract

Background: Laryngoscopy and endotracheal intubation is usually associated with hemodynamic changes increases in blood pressure and heart rate. We aimed to compare the hemodynamic effects of combined use of low dose thiopentone and propofol during induction of anesthesia with conventional dose of thiopentone and propofol separately.

Methodology: This trialwas conducted prospectively among90 candidates, American Society of Anaesthesiologists grade-l (ASA-I), scheduled for elective surgery, with an age range of 20-50 yearsSelected patients were randomly assigned to three equal groups. Thiopentone was used in group 1, propofol in group 2, and a combination of low dose thiopentone and propofol in group 3 as an induction agent.

Heart rate and blood pressures were measured non-invasively at five different times: prior to the injection of study drugs, three minutes after the last injection of induction drug and immediately before the laryngoscopy and endotracheal intubation, as well as at the first, third and fifth minutes after endotracheal intubation.

Published
02-04-2019
How to Cite
Lahsaee, M., Kamalipour, H., Ajeli, Z., & Kamali, K. (2019). A comparison of hemodynamic changes during laryngoscopy and endotracheal intubation by using three modalities of anesthesia induction. Anaesthesia, Pain & Intensive Care, 247-251. Retrieved from https://mail.apicareonline.com/index.php/APIC/article/view/525
Section
Original Articles