Does intra-cuff alkalinized lidocaine prevent tracheal tube induced emergence phenomena in children?

  • Mona S. Ahmady Department of Anesthesiology, Mansoura University, Mansoura (Egypt)
  • Sayed Sadek Department of Anesthesiology, El-Fayoum University, El-Fayoum (Egypt)
  • Roshdi R. Al- metwalli , Department of Anesthesiology & Intensive Care, University of Dammam (KSA)
Keywords: Lidocaine, Alkalinization, Post-extubation, Tracheal tube cuff, Laryngospasm

Abstract

Aim: To study and investigate the efficacy of intra-cuff alkalinized lidocaine in the prevention of the endotracheal tube (ETT) induced emergence phenomena in children.

Methodology: Fifty children, ages 6-12 years, ASA physical status I-II, scheduled for elective dental surgery under N2O free general anesthesia with an expected duration of 120 min or more, were randomly assigned one of the two groups (25 patients each); lidocaine group in which the cuff of ETT was inflated with a mixture of lidocaine 2% and sodium bicarbonate 8.4% and the saline group, in which tube cuff was inflated with 0.9% saline solution.

Results: There were significant reduction in the incidence and severity (p=0.005 & p= 0.014) of cough at extubation and in the PACU (P=0.048 & P=0.014). The incidence and severity of postoperative sore throat was also reduced in the lidocaine group compared to the saline group (p=0.025 and 0.031 respectively). Moreover, there was a significant prolongation of the time to spontaneous ventilation before extubation in the lidocaine compared to the control group (16.4±3.1 min and 9.4±1.7 min respectively) with p value < 0.0001.

Conclusion: Intra-cuff alkalinized lidocaine reduces the incidence of cough, sore throat, improved ETT tolerance and inducing smooth extubation in paediatric patients, but prolongs time to spontaneous ventilation before extubation.

Citation: Ahmady MS, Sadek S, Al-metwalli RR. Does intra-cuff alkalinized lidocaine prevent tracheal tube induced emergence phenomena in children? Anaesth Pain & Intensive Care 2013;17(1):18-21

Published
01-30-2019
How to Cite
Ahmady, M. S., Sadek, S., & metwalli, R. R. A.-. (2019). Does intra-cuff alkalinized lidocaine prevent tracheal tube induced emergence phenomena in children?. Anaesthesia, Pain & Intensive Care, 18-21. Retrieved from https://mail.apicareonline.com/index.php/APIC/article/view/475
Section
Original Articles