The link between migraine and eye pain: a review of current evidence

  • Mujeeb Ur Rehman Parrey
  • Maha M Abdul-Latif
  • Muhammad Omer Afzal Bhatti
  • Hafiz Osman Ibnidris Almisbah
  • Ahmed Hamad Ahmed Sulaiman
  • Omaima A Hamid MD
  • Mohammed M. Ismail
Keywords: Quality of Life, Dry Eye Disease, Trigeminal Neuralgia, Ocular Manifestations, Diagnostic Challenges, Pathophysiology, Cluster Headache, Migraine, Eye Pain

Abstract

Eye pain is a frequent and distressing symptom in individuals with migraines, yet it remains an underexplored aspect of migraine pathology. This review consolidates current knowledge on the association between eye pain and migraines, covering pathophysiological mechanisms, clinical features, differential diagnoses, and management approaches. A thorough analysis of existing literature indicates that migraine-related eye pain is multifactorial, involving neural, vascular, and sensory pathways. Additionally, this review underscores the need for further research to refine diagnostic criteria and enhance treatment strategies for patients experiencing ocular discomfort during migraine episodes.

Key words: Eye Pain; Migraine; Cluster Headache; Pathophysiology; Diagnostic Challenges; Ocular Manifestations; Trigeminal Neuralgia; Dry Eye Disease; Quality of Life

Citation: Parrey MUR, Abdul-Latif MM, Bhatti MOA, Almisbah HOI, Sulaiman AHA, Omaima A Hamid OA, Ismail MM. The link between migraine and eye pain: a review of current evidence. Anaesth. pain intensive care 2025;29(3):681-688. DOI: 10.35975/apic.v29i3.2772


Received: February 05, 2025; Revised: February 25, 2025; Accepted: March 06, 2025

Published
06-10-2025
Section
NARRATIVE REVIEW

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