A randomized prospective comparative study between intrathecal chloroprocaine 1% and ropivacaine 0.5% for short duration surgery

Abstract

Background and Objectives: Spinal anesthesia (SA) has recently seen a rapid surge in is popularity due to its edge over general anesthesia, being easier, cost-effective, lack of addictive drugs, reduced analgesic demand in the post anesthesia care unit, less nausea and vomiting within 24 h postoperatively, and a shorter hospital stay. Research continues regarding the best and the safest drug to be used for SA. We compared chloroprocaine 1% and ropivacaine 0.5% for SA in short duration surgery.

Methodology: A total of 70 patient were enrolled and subdivided into two groups; Group R (35 patients), to receive 4 ml of 0.5 % ropivacaine (20 mg) and Group C (35 patients), to receive 4 ml of 1% chloroprocaine (40 mg). Hemodynamic parameters and block characteristics were compared between the two groups.

Conclusion: This study shows that chloroprocaine 1% and ropivacaine 0.5% are equally effective in spinal anesthesia. However, chloroprocaine 1% is better suitable for shorter duration surgeries.

Key words: Chloroprocaine; Ropivacaine; Hemodynamics; Block Characteristics

Citation: Prakash V, Jain P, Prasad MK. A randomized prospective comparative study between intrathecal chloroprocaine 1% and ropivacaine 0.5% for short duration surgery. Anaesth. pain intensive care 2023;27(4):508−513; DOI: 10.35975/apic.v27i4.2260

Received: March 13, 2023; Reviewed: May 22, 2023; Accepted: May 22, 2023