Dexmedetomidine improves surgical field in cochlear implant surgery: a randomized, double-blind, placebo-controlled trial

  • Nishith Govil Department of Anesthesiology, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (India)
  • Shalini Dadu Department of Anesthesiology, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (India)
  • Virender P Singh Department of Otolaryngology, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (India)
  • Vinay Rai Department of Otolaryngology, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (India)
  • Parag Kumar Department of Anesthesiology, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (India)
Keywords: Dexmedetomidine, Cochlear implant, Pediatric patients

Abstract

Objectives: Sympatholytic properties of dexmedetomidine have many advantages to use in general anesthesia especially in pediatric age group undergoing cochlear implant surgeries. This study is designed to compare the effects of bolus dose of dexmedetomidine followed by infusion with placebo in cochlear implant surgeries for quality of hypotensive anesthesia with hemodynamic stability and incidence of complications in pediatric age group particularly emergence delirium with sevoflurane.

Methodology: 60 pediatric patient of ASA grade I or II with congenital or acquired deafness of age ranging from 2 to 8 years scheduled for cochlear implant surgery were included in this study.

Group D were administered dexmedetomidine 0.5 μg/kg in 100 ml 0.9% NaCI over 10 min followed by infusion of dexmedetomidine at 0.5 μg/kg/h and Group P was given placebo only i.e. 0.9% NaCl 100 ml over 10 min followed by infusion at 2 ml/h. Heart rate (HR) and mean arterial pressure (MAP) at different time interval, intraoperative fentanyl and propofol consumption, surgeons’ satisfaction score and complications, particularly incidences of emergence delirium were recorded.

Statistical analysis: Mean with standard deviation of various parameters of both groups was compared using student’s t test were analyzed.

Published
01-19-2019
How to Cite
Govil, N., Dadu, S., Singh, V. P., Rai, V., & Kumar, P. (2019). Dexmedetomidine improves surgical field in cochlear implant surgery: a randomized, double-blind, placebo-controlled trial. Anaesthesia, Pain & Intensive Care, 147-153. Retrieved from https://mail.apicareonline.com/index.php/APIC/article/view/118
Section
CLINICAL INVESTIGATION